Simparica for Dogs: Flea & Tick Medication

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Frequently Asked Questions

Simparica® (Sarolaner) is a chewable that kills adult fleas, and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis), and the treatment and control of tick infestations [Amblyomma americanum (lone star tick), Amblyomma maculatum (Gulf Coast tick), Dermacentor variabilis (American dog tick), Ixodes scapularis (black-legged tick), and Rhipicephalus sanguineus (brown dog tick)] for one month in dogs 6 months of age or older and weighing 2.8 pounds or greater.

Simparica is for dogs 6 months of age and older, and weighing 2.8 pounds or greater.

  • No messy application

  • Protects dogs and tick and fleas

  • Only monthly tick and flea chewable approved to kill 5 types of ticks, including the Gulf Coast Tick.

  • Great-tasting liver flavored chewable that you give your dog once a month.

The active ingredient in Simparica, sarolaner, works on the nervous system of fleas and ticks, causing hyperexcitation and death.

Simparica is a chewable that is given orally and can be given with or without food.

Simparica® kills adult fleas, and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis), and the treatment and control of tick infestations [Amblyomma americanum (lone star tick), Amblyomma maculatum (Gulf Coast tick), Dermacentor variabilis (American dog tick), Ixodes scapularis (black-legged tick), and Rhipicephalus sanguineus (brown dog tick)] for one month in dogs.

Treatment with Simparica may begin at any time of the year. In areas where fleas are common year-round, monthly treatment should continue the entire year without interruption. To minimize the likelihood of flea reinfestation, it is important to treat all animals within the household (along with the environment) with an approved flea product.

Simparica comes in a liver-flavored chewable.

If fleas or ticks are already present, discuss what other control measures should be used. Talk about what flea products to use on any other pets in the household, since all pets should be treated if there is an infestation. Have your veterinarian explain the life cycle of the flea and how that influences the effectiveness of monthly flea products.

Simparica should be used with caution in dogs with a history of seizures. The safety of Simparica has not been evaluated in pregnant, lactating or breeding dogs. Tell your veterinarian if your pet has epilepsy, could be pregnant, is lactating or is used for breeding.

As with any medication, notify your veterinarian of any other medications or supplements your pet is taking, and also if your pet has had any reactions to previous medications or supplements.

If you miss a dose, give it as soon as you remember, then resume giving it every 30 days (once a month). If it is almost time for the next dose, skip the one you missed and go back to the regular schedule. Do not give 2 doses at once. If you are unsure whether to give a dose, contact your veterinarian.

Precautions
Sarolaner is a member of the isozaxoline class. This class has been associated neurologic adverse reactions including tremors, ataxia and seizures. Seizures have been reported in dogs taking isozaxoline class drugs, even in dogs without a history of seizures. Use with caution in dogs with a history of seizures or neurologic disorders. The safe us of Simparica has not been evaluated in breeding, pregnant or lactating dogs.

May see vomiting, diarrhea, lethargy or lack of appetite. Consult your veterinarian if you notice any of the above side effects.

If your pet experiences an allergic reaction to the medication, signs may include facial swelling, hives, scratching, sudden onset of diarrhea, vomiting, shock, seizures, pale gums, cold limbs, or coma. If you observe any of these signs, contact your veterinarian immediately.

Store at or below 86 degrees Farenheit. Keep out of reach of children and pets.