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My dog mated. Why no blood or discharge after Depo-Provera shot?

Updated on September 23, 2025

Pet's info: Dog | Mixed Breed Medium (23 - 60lb) | Female | unspayed | 30 lbs

Yesterday stela mated with a stray dog at 8:15pm and i called the vet and he told me to pass by to pick the depo-progevera syrenge. I passed and picked up it at 6:45 and i give it to her. But i didnt notice any blood or discharge in her genital why?

1 Answer

Most Helpful Answer

Rodrigo Roca, DVM

Answered By Rodrigo Roca, DVM

Veterinarian

Published on July 11, 2018

Hello, this is a hormone that prevents ovulation and thereby pregnancy. It should not cause any bloody discharge from her vulva after being administered. Additionally, it may take several hours to have full effect and the effects may last up to 3 months.

This medication does have multiple side effects in dogs, so you may see an increased in thirst and urination. Dogs could develop hair loss at the site of injection. Dogs can also develop enlarged mammary glands but this does not necessarily mean they are pregnant.

If you see any of these side effects, or if Stela does not seem well, then have your veterinarian examine her. Hope this helps and best of luck.
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