Sileo Dog Medicine and Prescriptions | Petco

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Is Sileo, a dog sedative, safe for my cat's travel anxiety?
Hello. Yes, the medication in Sileo is used in cats all the time, but actually using this particular product in cats is considered extra-label & therefore you are using this at your own risk. Since the smallest amount that can be dispensed from the tube is one dot, I assume that is the maximum that anyone would want to use on a cat, but PLEASE contact your pharmacy or your veterinarian for the exact amount to be used. Otherwise, I can not recommend the use of Sileo in cats. Thanks for using Petco Pet Education Center, formerly Petcoach.
Updated on September 24th, 2025
Training & Behavior
My dog has noise anxiety. What medications or supplements help?
There are prescription medications that can help with noise anxiety in dogs, such as Sileo, alprazolam, or trazodone - but you will need to discuss this with your veterinarian, since he/she will have to be the one to prescribe the meds if they feel this would be a good option for Tiger. You could also try a natural calming supplement like Zylkene or Composure, and/or a DAP pheromone collar to help relieve some of his anxiety. These can be ordered online without a prescription, and are generally quite safe to use in any dog.
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Can I get a Bravecto flea pill prescription for my small dog online?
Unfortunately it is illegal for us to prescribe any medication from this site. It's also against the user terms of the site. You need to have Selena seen by a vet in person to get a prescription for Bravecto.
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How do I order my dog's vet prescription meds online from Petco?
You would need a current prescription from a veterinarian who has physically examined Duke. You can then place your order and submit the prescription. The pharmacy will then contact the veterinarian or clinic to confirm the prescription then fill the order.
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My dog's Acepromazine isn't working for anxiety. Can I increase dose?
Unfortunately Acepromazine does not take away fear and anxiety. It just sedates the dog, he will appear quieter, but inside, she is just as anxious, just cannot express it. There is a much better medication for that and it is called Sileo. Your veterinarian can provide you with that and give you the proper dosage for Bella. We are not in a position legally to give out dosages. In order to do legally so we would have to have a patient-veterinarian-owner relationship with you. Your veterinarian also knows your dog and the potential risks for your dog receiving acepromazine.
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