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Ultimately, this is a decision that really needs to be made by the prescribing veterinarian, as there may be good reasons for choosing one of these medications over the other for a particular patient. But in general, I can tell you that most veterinary behaviorists prefer SSRIs like fluoxetine over older TCAs like amytriptyline as a first-line choice for anxiety issues in cats because they tend to have fewer side effects and are better tolerated by most patients. I personally use fluoxetine frequently in both dogs and cats, and have not prescribed amirtiptyline in years. But again, your vet may have good reasons for whichever medication they recommend - just ask, and express your concerns if you have any so that the two of you can come to the best decision for Fiona :)
Updated on September 24th, 2025

Thank you for using Petco Pet Education Center, formerly Petcoach! Prozac, or the generic medication fluoxetine is safe for dogs, even with heart murmurs. It may cause slight sedation. Natural products may not be as reliably effective, and may also cause sedation. These should also not have any affect on Bradley’s murmur. I definitely recommend avoiding giving both natural chews and Prozac at the same time. I hope this helps and am happy to answer any other questions you have!
Updated on September 24th, 2025

This is a difficult question, as the recommendation for which medications or therapies to start for anxiety are very individualized to the patient and the specific things that are triggering their episodes. If you haven't tried some over-the-counter therapies such as a Thundershirt ( https://www.petco.com/shop/en/petcostore/product/thundershirt-heather-gray-dog-anxiety-solution ) or a pheromone diffuser ( https://www.petco.com/shop/en/petcostore/product/thunderease-calming-diffuser-kit-for-dogs ) those are often good places to start. If these aren't helping you will need to consider consulting with a vet, who can prescribe Prozac or another anxiety medication, along with behavior modification therapy.
Updated on September 24th, 2025

I would discuss this issue with your veterinarian. We definitely do not want to stop the Prozac suddenly as he could develop withdrawal symptoms. Other supplements that could help include Zylkene or a prescription cat food like c/d® Multicare Stress Feline. Acupuncture is another alternative method that may help with stress and urinary issues in cats.
Updated on September 24th, 2025

Hello. You can try Zylkene ( httpe://www,vetoquinolusa.com ) or ProPlan calming care ( https://www.proplanveterinarydiets.com/products/calming-care-dog-probiotic-supplement/ ). Hope one of these is helpful for Hachi. Thanks for using PetCoach.
Updated on September 24th, 2025