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Thank you for contacting Petco Pet Education Center with your question. Twenty mg of fluoxetine given once daily to a 47lb dog is within the recommended dose range, so yes it is safe. The trazadone dose is also within the recommended dose range when used in combination with a selective serotonin reuptake inhibitor, which is the classification of fluoxetine. There is n increased risk of developing a disorder called serotonin syndrome when these two drugs are used together, but the lower dose range of trazadone is used when they are given together to try to prevent that. The normal dose range of trazadone is higher than what Hank is currently being given. I hope this helps!
Updated on September 24th, 2025
I'm not 100% sure about the stability of fluoxetine outside of the capsule, but as long as a capsule is not extended release I will sometimes recommend that people put the contents in a meatball like you describe for pets who are difficult to pill. I would be concerned about the stability of the drug in the meatball for 10 days however - it would probably be best to make each meatball daily and leave the remaining medication in the capsule or a dark plastic bag so it isn't exposed to light or oxygen. You may also want to ask your vet about having the medication compounded into a liquid suspension through a compounding pharmacy which might make it easier to squirt into a meatball and would result in more accurate dosing.
Updated on September 24th, 2025
Based on the normal dose range of fluoxetine for dogs, your dog received less than double the recommended dose. Signs of overdose include lethargy and hyper salivation, while seizures can occur in dogs who have massive overdoses (this would not be considered a massive overdose). Because your dog has only taken a little over the highest recommended dose, he should be ok but you can take him into a vet to have vomiting induced to be safe. I never recommend doing it at home due to the risk of aspiration and the fact that hydrogen peroxide (which people commonly use at home to induce vomiting) can and does cause gastritis often worse than the initial problem. You can monitor him, and you do see any side effect, you can take him into the vet.
Updated on September 24th, 2025
I usually don't expect to see positive changes for at least 6 weeks. You may want to discuss these side effects with your vet to see if there might be a better anxiety medication to use - there is no one best medication for all dogs, sometimes it is trial and error. I can't really tell you what to expect next, since every dog is so different. I would not expect that his current side effects would get worse, though.
Updated on September 24th, 2025
Hi there. The published dosage range for fluoxetine (Prozac) in dogs is 0.5 - 2 mg/kg once daily. 60 mg is within this range, but this medication is normally given only once daily. Your veterinarian may have had a specific reason for choosing to prescribe it twice daily in Saber's case, so if you're concerned, I would recommend calling to discuss your questions with your vet. He/she should be able to explain why they chose this dosage for Saber, or may opt to reduce it if it was an oversight :)
Updated on September 24th, 2025