Tri-Heart Plus Chewables for Dogs

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Frequently Asked Questions

This monthly oral pet med is used as a combination heartworm preventive and intestinal wormer. Tri-Heart Plus kills the immature form of the heartworm (Dirofilaria immitis), which is transmitted by a mosquito. It is also used for the treatment and control of hookworms (Ancylostoma caninum, A. brasiliense, and Uncinaria stenocephala) and roundworms (ascarids - Toxocara canis, Toxascaris leonina).

Dogs and puppies over 6 weeks of age. Safe for pregnant/breeding females.

  • Tasty medicine used for both heartworm prevention and intestinal worming

  • Economical heartworm medication with the same active ingredients as Heartgard Plus

  • Give year round for complete protection

Tri-Heart Plus is used in the prevention of heartworm infection and the control and treatment of various other worm infections. Tri-Heart Plus contains two active ingredients: ivermectin, which interferes with the parasite's nerve transmission, causing paralysis and death of the immature heartworms (larvae), and Pyrantel pamoate, which also interferes with the parasite's nerve transmission, causing paralysis and death of intestinal worms.

Yes, both the Tri-Heart Plus and Iverhart Plus are branded generic alternatives to Heartgard Plus and should be interchangeable as long as the doctor does not indicate "dispense as written".

Tri-Heart Plus must be administered monthly, preferably on the same date each month. It is recommended (and most manufacturer guarantees require) that Tri-Heart Plus be given year-round, although some veterinarians may recommend giving it only during the mosquito season. If given seasonally, the first dose must be given within 30 days of the dog's first exposure to mosquitoes. The last dose must be given within 30 days after the dog's last exposure to mosquitoes.

Most dogs like the taste of Tri-Heart Plus and will accept the chewable tablet as a treat. The chewable should be administered in a manner that encourages the dog to chew, rather than to swallow without chewing. Tri-Heart Plus Chewables may be broken into pieces and fed to dogs that normally swallow treats whole. Care should be taken that the dog consumes the complete dose, and treated animals should be observed for a few minutes after administration to ensure that part of the dose is not lost or rejected. If not entirely consumed, give another full-recommended dose as soon as possible.

Tri-Heart Plus will kill the immature heartworms the dog was exposed to in the preceding month. It will treat an intestinal infection with adult hookworms and roundworms.

All dogs should be tested for existing heartworm infection before starting treatment with Tri-Heart Plus chewable tablets which are not effective against adult D. immitis. Infected dogs must be treated to remove adult heartworms and microfilariae before initiating a program with Tri-Heart Plus chewable tablet.

Collies or other herding breeds may have a reaction to ivermectin if given over the recommended heartworm prevention dose. If your dog is one of these breeds, and your veterinarian has prescribed Tri-Heart Plus, observe your pet for at least 8 hours after giving the medication for weakness, staggering, dilated pupils, trembling, drooling, or pressing the head against a wall. Contact your veterinarian immediately if you see these signs.

Some intestinal parasites, such as hookworms and roundworms can be spread to people. Talk to your veterinarian about other measures you can take to prevent your pet from being infected with intestinal worms, and protecting yourself.

Notify your veterinarian of any other medications or supplements your dog is taking, and if your dog has had any reactions to previous medications.

If a dose is missed and over 30 days have gone by since the last dose, give Tri-Heart Plus immediately and resume a monthly dosing schedule. Tell your veterinarian that a dose was missed.

If the interval between doses is longer than one month, the efficacy of the drug is reduced.

Do not use in puppies less than 6 weeks of age. Considered to be safe to use in pregnant and lactating animals (female animals nursing their young).

Collies and herding breeds may have a reaction to Tri-Heart Plus.

This medication should only be given to the pet for which it was prescribed.

Side effects of Tri-Heart Plus are very rare, but may include vomiting and diarrhea. Even more uncommon are incoordination, convulsions, or drooling. Contact your veterinarian if you observe any of these side effects.

Store between 68°F-77°F (20°C-25°C). Short periods between 59°F-86°F (15°C-30°C) are permitted. Protect product from light. The chewable form of the drug is appealing to pets and children. Store in a secure area to prevent an accidental overdose. Keep out of reach of children and pets.

If you know or suspect your pet has had an overdose, or if you observe diarrhea, vomiting, incoordination, convulsions or drooling, contact your veterinarian immediately.

Although there are no known drug or food interactions with this medication, consult with your veterinarian before using Tri-Heart Plus with any other medications, including vitamins and supplements, since interactions may occur.