All dogs should be tested for existing heartworm infection before starting treatment with Tri-Heart Plus chewable tablets which are not effective against adult D. immitis. Infected dogs must be treated to remove adult heartworms and microfilariae before initiating a program with Tri-Heart Plus chewable tablet.
Collies or other herding breeds may have a reaction to ivermectin if given over the recommended heartworm prevention dose. If your dog is one of these breeds, and your veterinarian has prescribed Tri-Heart Plus, observe your pet for at least 8 hours after giving the medication for weakness, staggering, dilated pupils, trembling, drooling, or pressing the head against a wall. Contact your veterinarian immediately if you see these signs.
Some intestinal parasites, such as hookworms and roundworms can be spread to people. Talk to your veterinarian about other measures you can take to prevent your pet from being infected with intestinal worms, and protecting yourself.
Notify your veterinarian of any other medications or supplements your dog is taking, and if your dog has had any reactions to previous medications.