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Galliprant for Dogs

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Frequently Asked Questions

Galliprant (grapiprant tablets) is a prescription medication indicated for control of pain and inflammation due to osteoarthritis in dogs.

Osteoarthritis (OA) is a condition where cartilage - the protective material that cushions a joint - breaks down over time, causing the bones to rub against each other. This rubbing can permanently damage the joint and cause pain, inflammation, and lameness. Older and overweight dogs are at a higher risk of developing OA.

Other NSAIDs that are FDA-approved for use in dogs include deracoxib (Deramaxx), carprofen (Rimadyl, Novocox, Carprieve, Quellin, Carprofen), meloxicam (Metacam, Loxicom, Orocam, Meloxidyl, Meloxicam), and firocoxib (Previcox).

At this time there is no generic equivalent for Galliprant. Galliprant is the only available form of grapiprant.

Galliprant (grapiprant) should only be given to dogs. Not for use in dogs younger than 9 months and less than 8 pounds. Do not use in cats. Not to be used in humans.

Galliprant (grapiprant) is available in tablets that are given orally (by mouth). These tablets contain desiccated pork liver as the flavoring agent. Always follow the dosing instructions provided by your veterinarian. If you have difficulty giving this medication, contact your veterinarian. This medication should only be given to the pet for whom it was prescribed.

Grapiprant is a prostaglandin E2 (PGE2) EP4 receptor antagonist; a non-cyclooxygenase (COX) inhibiting, non-steroidal anti-inflammatory drug (NSAID) in the piprant class.

Galliprant (grapiprant) targets canine osteoarthritis pain and inflammation while reducing the impact on the gastrointestinal (GI) tract, kidneys, and liver. All NSAIDs carry certain risks, including vomiting, diarrhea, not eating/eating less, and lethargy.

The most common adverse reactions to Galliprant include vomiting, soft, mucoid stools, diarrhea, and decreased appetite. Contact your veterinarian if your dog's appetite decreases or stools become abnormal. Adverse reactions may also include decreasing serum albumin and total protein.

Galliprant is not for use in dogs taking other non-steroidal anti-inflammatory drugs (NSAIDs) or corticosteroids (for example, aspirin, carprofen, meloxicam or prednisone). As with any NSAIDs, if Galliprant is used long-term, appropriate monitoring (including blood testing) is recommended.

Galliprant is not for use in dogs that have had an allergic reaction (such as hives, facial swelling, or itchy skin) to Galliprant. Tell your veterinarian if your dog has had an allergic reaction to Galliprant or other anti-inflammatory drugs.

Not for use in humans. For use in dogs only. Keep out of reach of children and pets. Monitoring is recommended if used long term. Should not be used in dogs who are allergic to grapiprant or with other anit-inflammatory drugs. The safe use of Galliprant has not been studied in dogs younger than 9 months of age and less than 9 pounds, breeding, pregnant or lactating dogs, or dogs with heart disease. The most common adverse reactions were vomiting, diarrhea, decreased appetite and tiredness. Please see Galliprant label for full safety information.

Tell your veterinarian about any side effects or adverse reactions your dog has experienced from Galliprant or other NSAIDs. Tell your veterinarian about any other medical problems or allergies that your dog has had.

Store at or below 86°F (30°C). Store this and all medications out of reach of children and pets, to prevent accidental ingestion or overdose.

If you miss a dose, give it as soon as you remember. If it is almost time for the next dose, skip the one you missed and go back to the regular schedule. Do not give two doses at once.

If you know or suspect that your pet has had an overdose, contact your veterinarian immediately.

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