Description

Calmera (clomipramine hydrochloride) Tablets for Dogs. Softened, scored tablet for easy and accurate dosing. Beef flavored for palatability. Can be administered as single dose or twice-daily split dose. Broad dosing range supports intermediate-weight dogs, decreasing the need to split tablets. Calmera (clomipramine hydrochloride) Tablets are indicated for the treatment of generalized and separation-related anxiety in dogs greater than 6 months of age. Calmera Tablets are to be used as part of a comprehensive behavioral management program. The use of Calmera Tablets should not replace appropriate behavioral and environmental management but should be used to facilitate a comprehensive behavior management program. Please follow your pet's individual treatment plan, which may include a combination of medications and behavioral modification strategies, as recommended by your veterinarian or animal behaviorist.

• - Calmera tablets are contraindicated in dogs with known hypersensitivity to clomipramine or other tricyclic antidepressants. Calmera tablets are contraindicated for use in dogs with a history of seizures or concomitantly with drugs which lower the seizure threshold. Calmera tablets should not be used in male breeding dogs nor should it be given in combination, or within 14 days before or after treatment with a monoamine oxidase inhibitor. Refer to label or insert for precautions, warnings, dosing and administration, and storage information. Product sourced directly from the manufacturer or their approved distributor. Guaranteed genuine product backed by the manufacturer. For: Dogs. Active ingredient(s): Clomipramine hydrochloride. Drug class: Tricyclic antidepressant. Product flavoring: Beef flavored. Contains meat components, the exact components are not specified by the manufacturer. Calmera is supplied as softened, scored tablets and are available in multiple tablet strengths
• - Please ensure the selected product and quantity are appropriate for your pet, as recommended by your veterinarian. For current availability, please refer to the product selection above. Usage: Calmera Tablets should be administered as directed by your veterinarian. Do not discontinue abruptly. Please consult your veterinarian before making any changes or discontinuing the prescribed dosing schedule. If you have questions about your pet's prescribed dosing schedule (e.g., timing, interval), please contact your veterinarian. Manufacturer Dosage and Administration: The recommended daily dose of CALMERA tablets is 2 to 4 mg/kg/day (0.9 -1.8 mg/lb/day). To reduce the incidence of vomiting that may be experienced by some dogs, CALMERA tablets may be given with a small amount of food. If a dose is missed, the next dose should be administered (without doubling) at the next scheduled dosing time. Additional information may be provided within the manufacturer's full Prescribing Information
• - Always follow the specific instructions provided by your veterinarian regarding your pet's care. Storage: Store in a cool, dry place at a controlled room temperature between 59 and 77F. Store unused tablets in the original closed container. Keep this and all other medications in a secure location out of the reach of children and animals. Exposure to extreme temperatures, light, or moisture can affect the integrity and effectiveness of medications. Always store this medication properly (e.g., away from the bathroom, kitchen sink, or other damp places). Side effects: The most common side effects of this medication are vomiting, lethargy, diarrhea, increased thirst, and decreased appetite. Contact your veterinarian immediately if your pet experiences severe vomiting or diarrhea, convulsions or seizures, trouble urinating, extreme behavioral changes (e.g., overexcitement, aggression), or weakness and incoordination. The information provided above may not encompass all possible side effects
• - Please notify your veterinarian if your pet experiences any side effects, including those listed above, or if you notice anything unusual. Precautions: Before using this product, please review the manufacturer's full Prescribing Information for any relevant warnings and safety precautions. For oral use in dogs only. Not for use in humans. Keep this and all medications out of reach of children and animals. In case of accidental ingestion, seek medical attention immediately. People with known hypersensitivity to clomipramine should administer the product with caution. Do NOT use this medication in male breeding dogs or in dogs with a history of seizures. Clomipramine should not be given in combination, or within 14 days before or after treatment with a monoamine oxidase inhibitor (e.g., amitraz, selegiline). Therefore, it is NOT compatible with flea and tick collars that contain amitraz as an active ingredient
• - If your pet is currently using one of these collars, consult your veterinarian before starting this medication. Use with caution in dogs with cardiovascular disease, preexisting liver disease, urinary retention, glaucoma, or reduced GI motility. Safe use of this medication has not been evaluated in pregnant or lactating female dogs. Discuss the risks of using this medication with your veterinarian prior to use if your pet is in one of these groups. Do not administer this medication to animals with a known or suspected allergy/hypersensitivity to any tricyclic antidepressant, including clomipramine, or to any other ingredient in the formulation. Allergic reactions to medications may occur. Please inform Vetsource and your veterinarian if your pet has any known sensitivities or allergies, especially to medications and supplements. If your pet displays symptoms of an allergic reaction, discontinue therapy and call your veterinarian immediately or seek emergency veterinary attention
• - Symptoms may include (but are not limited to): swollen lips, tongue, face, or airways, difficulty breathing, agitation, profuse salivation, and widespread hives or itching. Food and drug interactions: The following drugs may have potential interactions with this medication: acepromazine (PromAce), anticholinergic drugs (e.g., amantadine, atropine), antihistamines (e.g., hydroxyzine), blood pressure medications (e.g., enalapril, sildenafil, telmisartan), dexmedetomidine (Sileo), levothyroxine, MAOIs (e.g., amitraz, selegiline), methocarbamol, metoclopramide, mirtazapine, ondansetron, phenobarbital, phenylpropanolamine (Proin), sotalol, SSRIs (e.g., fluoxetine), tramadol, and trazodone. NOTE: This may not be a comprehensive list. As with all medications, please consult your veterinarian if you have any questions or concerns prior to use. Contact your veterinarian if your pet experiences any unusual reactions when multiple medications and/or supplements are given together
• - Please ensure your veterinarian is aware of all medications, supplements, and over-the-counter products that your pet is currently using. If you are concerned that your pet has experienced an adverse reaction to this medication, please contact the manufacturer at 1-561-570-1875 or Vetsource Pet Owner Care at 877-738-4443. If you have any reason to suspect accidental ingestion or overdose, call your doctor/veterinarian or the appropriate poison control resource immediately. For humans:The national toll-free Poison Help line, 1-800-222-1222, will connect you to your local poison center in case of emergency. This service is available nationwide and in most U.S. territories. For animals:The ASPCA Animal Poison Control Center is available 24 hours a day, 365 days a year at 888-426-4435. Pet Poison Helpline also provides a 24/7 animal poison control service at 855-764-7661. The contact information provided above is for third-party services in the event of a potential poison-related emergency