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Potassium Bromide for Dogs: Seizure Prevention & Epilepsy Relief

Published on September 10, 2024
Updated on November 5, 2025
Reviewed by Petco's Veterinarian Team

Anticonvulsant used either alone or with other anticonvulsants to control seizures in epileptic dogs.

Summary

Used For:

To control seizures in epileptic dogs

Brands:

K-Brovet, Libromide

Species:

Dogs

Other names:

KBr, bromide salts

Drug type:

Anti-seizure

Prescription required:

Yes

Pregnancy and lactation:

Safety in pregnant and lactating animals has not been established

Side effects:

Sedation, increased appetite, weight gain, increased thirst and urination, stumbling/incoordination

General description

Potassium bromide is an anticonvulsant medication most commonly used to control epileptic seizures in dogs. Potassium bromide may be used alone or in conjunction with other anticonvulsants.

Buy Potassium bromide now on Petco. A prescription from your veterinarian is needed to purchase.

Uses

To control seizures in epileptic dogs

How it works

Potassium bromide works by replacing negatively charged chloride ions through the chloride channels causing neuronal hyperpolarisation which decreases or prevents seizures. Potassium bromide can be used alone or with other anticonvulsants to control seizures in epileptic dogs.

Dosage

Dogs: 15-40 milligrams per kilogram of body weight by mouth once daily with food (maintenance dose). A loading dose is given initially, 400-600 milligrams per kilogram of body weight given by mouth divided into several doses per day for 1-5 days before lowering the dose to the maintenance dose.

The medication dosages listed represent the variation in dosing for all underlying medical conditions.

Medications should only be administered to pets under the direct guidance of a veterinarian.

Forms

Potassium bromide is available in 200, 250, 325 and 500 milligram tablets for oral use. Potassium bromide is also available in a 2 ounce per 59 milliliter oral solution and a 10 ounce per 300 milliliter oral solution.

Storage information & handling

Store in tight containers. Solutions should be stored in clear or brown, glass or plastic containers at room temperature. Solutions may be stored for up to one year.

What results can I expect?

Some dogs may experience sedation (drowsiness) when first starting this medication. This often resolves within several weeks of starting the medication. Some dogs also experience an increased thirst, which causes increased urination, and an increased appetite which can cause weight gain. Pet parents should see fewer seizures while their pet is receiving potassium bromide. Talk to your veterinarian if your pet continues to have seizures or any side effects associated with potassium bromide.

Missed Dosage

Do not miss a dose of potassium bromide as seizures may result. Consult your veterinarian if a dose is missed.

Overdose / acute toxicity

Toxicity is more likely with chronic overdoses and death is not likely from an acute overdose. Signs of toxicity include:

  • Muscle pain
  • Neurological signs
  • Pupils of unequal size
  • Decreased or absent reflexes

Consult your veterinarian immediately if you suspect your pet has received an overdose of potassium bromide.

Side effects

May include:

  • Drowsiness
  • Increased appetite and weight gain
  • Increased thirst and urination
  • Behavior changes
  • Difficulty walking/stumbling/incoordination
  • Vomiting
  • Difficulty swallowing

Contraindications

*Not recommended for use in cats since KBr can cause severe negative pulmonary effects.

*Do not use in pets with a hypersensitivity to KBr.

Drug interactions

Potassium bromide may interact with:

  • Central nervous system sedating drugs
  • Diuretics
  • Intravenous fluids containing sodium
  • Low or high sodium diets
  • Drugs that lower the seizure threshold

Precaution

Older dogs and those with other diseases may not tolerate potassium bromide. Dogs with kidney dysfunction may require dosage adjustments.

Sources

Plumb’s Veterinary Drug Handbook

Disclaimer
The information contained on this page is for educational purposes only. This medication should only be given under the advice of a veterinarian who has examined your pet under the laws applicable to your state of residence.

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