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Methionine is an essential amino acid often used as a urinary acidifier in dogs and cats that are prone to struvite crystal formation.
Prevention of urinary crystals and stones
Acidigel, Methigel
Dogs and cats
Methio-Form, DL-methionine
Urinary
Yes
Safe use in pregnant or lactating animals has not been established.
Loss of appetite, vomiting, diarrhea, weakness, pale or blue mucous membranes, incoordination
Methionine is used as a urinary acidifier. It is used for the treatment and prevention of struvite urinary stones.
Struvite crystalluria
Struvite urinary crystals form when the urine is too alkaline. Methionine is metabolized into sulfuric acid in the body which is then expelled in the urinary tract. This acidifies the urine in the body which then decreases the likelihood of struvite crystal formation.
Dogs and Cats: 150-300 milligrams per kilogram given orally every 8 hours.
500 milligram tablets are available for animals.
Store tablets in a cool, dry place away from light.
Your veterinarian will want to monitor the pH of your pet’s urine while on this medication to ensure it’s working. Once the pH is normal, your veterinarian may adjust how often you give this medication. Struvite crystals may be a transient finding that does not require special care particularly in dogs. Struvite stones in dogs are most often the result of a urinary tract infection which cannot be prevented by urine acidification.
If a dose is missed, continue the next dose at the scheduled time.
Overdose can cause metabolic acidosis. This is a medical emergency.
If your pet receives an overdose, please seek immediate veterinary attention.
May include:
*Do not use in animals that are already on prescription urinary diets.
*Do not use in pets with liver, kidney or pancreatic disease.
No known drug interactions.
Do NOT use if the pet is on a special diet that also acidifies the urine unless directed by your veterinarian.
VIN Veterinary Drug Handbook
Disclaimer
The information contained on this page is for educational purposes only. This medication should only be given under the advice of a veterinarian who has examined your pet under the laws applicable to your state of residence.