Two Easy Ways to Start Earning Rewards!
Earn 2X Pals Rewards points at Petco
when you use Petco Pay!
An arsenic-containing compound used in the treatment of heartworm infections in dogs.
Used to treat heartworm infections in dogs
Immiticide, Diroban
Dogs
Anti-parasitic
Yes
Safe use in breeding, pregnant, or lactating dogs has not been evaluated.
Pain, swelling, and tenderness at the injection site. Coughing, gagging, depression, lethargy
Yes
Melarsomine is indicated for the treatment of stabilized heartworm disease caused by immature (4 month old, stage L5) to mature adult infections of Dirofilaria immitis in dogs.
Heartworm infections in dogs
Melarsomine contains arsenic which kills both the adult heartworm and immature heartworm greater than 4 months old.
Dogs
2.5 milligrams per kilogram of body weight deep intramuscular injection into the lumbar epaxial muscles (L3-L5) twice 24 hours apart (2-injection protocol) or 2.5 milligrams per kilogram of body weight deep intramuscular injection into the lumbar epaxial muscles (L3-L5) followed by two injections given 24 hours apart 1 month later (3-injection protocol).
50 milligram melarsomine powder in a vial for reconstitution with 2 milliliters sterile water.
Store at room temperature. Protect from freezing.
Use immediately or the solution may be stored under refrigeration and kept from light in the original vial and used within 24 hours.
Keep out of reach of children and animals.
Resolution of heartworm infection
Doses must be administered by a veterinarian according to treatment protocol.
Melarsomine has a low margin of safety. Signs of overdose include:
May include:
Do not use in dogs with:
Aspirin and CNS depressant drugs may interact with melarsomine.
Older dogs may be more susceptible to adverse effects than younger dogs.
Do not administer intravenously or subcutaneously as significant toxicity or tissue damage may occur.
Animals with other diseases should be treated only with intense monitoring.
The dog must be kept quiet (cage rest) for 4-6 weeks after treatment to help decrease the risk of pulmonary embolism.
Obtain an accurate body weight prior to treating.
Plumb’s Veterinary Drug Handbook
VIN Veterinary Drug Handbook
Disclaimer
The information contained on this page is for educational purposes only. This medication should only be given under the advice of a veterinarian who has examined your pet under the laws applicable to your state of residence.