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Marbofloxacin: Pet Antibiotic for Skin, UTI, Respiratory Infections

Published on September 10, 2024
Updated on November 5, 2025
Reviewed by Petco's Veterinarian Team
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Marbofloxacin is a broad spectrum quinolone antibiotic.

Summary

Used For:

Infections of the skin, urinary tract, respiratory tract, soft tissues, bone

Brands:

Zeniquin

Species:

Dogs and cats

Other names:

Marbocyl

Drug type:

Antibiotic

Prescription required:

Yes

Pregnancy and lactation:

Do not use in pregnant or lactating animals.

Side effects:

GI upset, dilated pupils, vision problems, lethargy, seizures, dizziness, anxiety, behavior changes

General description

Marbofloxacin is a quinolone antibiotic that is effective against many species of bacteria. It can also be effective against blood-borne infectious agents such as mycoplasma. Gastrointestinal side effects can occur as a side effect of this antibiotic.

Uses

To treat bacterial infections

How it works

Marbofloxacin works by stopping bacterial replication.

Dosage

Dogs and Cats: 2 - 5.5 milligrams per kilogram of body weight by mouth every 24 hours.

Forms

Marbofloxacin tablets for oral use are available in 25, 50, 100 and 200 milligram sizes.

Storage information & handling

Store tablets in a cool, dry place and out of direct sunlight.

What results can I expect?

Susceptible bacterial infections should start to clear during the course of treatment.

Missed Dosage

If a dose is missed, continue with the next dosage at the scheduled time.

Overdose / acute toxicity

Overdose can cause toxic effects to the central nervous system.

Side effects

May include:

  • Nausea
  • Diarrhea
  • Vomiting
  • Cartilage damage

Contraindications

Do not use in:

  • Young or growing animals
  • Pregnant animals or animals that are lactating
  • Animals that have seizures

Drug interactions

Do not use with theophylline.

Do not use with other drugs that contain aluminum.

Precaution

Do not use in pregnant or lactating animals.

Sources

Saunders Handbook of Veterinary Drugs

Disclaimer
The information contained on this page is for educational purposes only. This medication should only be given under the advice of a veterinarian who has examined your pet under the laws applicable to your state of residence.

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