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Lactulose for Dogs & Cats: Constipation & Hepatic Encephalopathy
LACTULOSE ORAL SOLUTION, 16 FL. OZ.
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Lactulose is a medication that lowers ammonia levels in the blood, often prescribed during liver dysfunction. It also creates water retention in the gastrointestinal tract to aid in constipation.
Summary
Used For:
Hepatic encephalopathy, constipation, obstipation
Brands:
Chronulac
Species:
Dogs and cats
Other names:
Enulose, Cephulac
Drug type:
Gastrointestinal
Prescription required:
Yes
Pregnancy and lactation:
Should be used with caution in pregnant and lactating animals.
Side effects:
Fluid and electrolyte loss
General description
Lactulose is a medication that is used as a stool softener to treat constipation in dogs and cats. It is used commonly in cats with megacolon. It may also be used in the treatment of liver disease in small pets and birds to help reduce ammonia that can build up in the blood due to liver disease.
Buy Lactulose now on Petco. A prescription from your veterinarian may be needed to purchase. While many medications are administered for ‘off-label’ or 'extra-label' use in veterinary medicine, it is important your veterinarian knows all vitamins, supplements, and medications your pet is taking. You must also be sure to follow all instructions provided by your vet carefully and consult your veterinarian with any questions or concerns if they arise.
Off- or extra- label use of a medication can only be done by a veterinarian who has direct and personal knowledge of your pet and when there are no other appropriate medications for a particular pet's circumstances.
Uses
Hepatic encephalopathy, hyperammonemia, constipation
How it works
Lactulose causes water retention in the intestine and lowers the pH of the colon.
Dosage
Dogs and Cats: 1 milligram per 4.5 kilograms of body weight given orally every 8 hours until no longer needed.
Forms
10 gram/15 milliliter liquid form.
Storage information & handling
Store solution in a tightly sealed container away from light.
What results can I expect?
Lactulose is used until results are seen. In cases of constipation, lactulose usually begins working as a laxative within 1-2 days. In cases of hepatic encephalopathy, ammonia decrease will depend on the severity of the liver disease.
Missed Dosage
Continue dose at the next scheduled time.
Overdose / acute toxicity
Overdose is rare, but it can cause excessive fluid loss and dehydration.
Side effects
May include:
- Diarrhea
- Increased gas
- Distention of the stomach (animal appears bloated)
- Stomach cramping
- At high doeses low blood potassium and/or high sodium blood levels may be seen
Contraindications
*Do not use in animals with allergies to this medication, pets with a gastrointestinal obstruction and should be used with caution in pets who are diabetic, pregnant or lactating, .or have a fluid electrolyte imbalance.
Drug interactions
Be sure to tell your veterinarian about any medications, supplements, vitamins or herbal supplements you are providing to your pet. Medications such as antacids, laxatives, neomycin, gentamicin, or warfarin should be used with caution.
Precaution
To prevent dehydration, make sure your pet has plenty of clean water to drink while being treated with lactulose.
Sources
Saunders Handbook of Veterinary Drugs
Disclaimer
The information contained on this page is for educational purposes only. This medication should only be given under the advice of a veterinarian who has examined your pet under the laws applicable to your state of residence.