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Griseofulvin is an antifungal used to treat ringworm infection in dogs, cats, and horses.
Treatment of dermatophyte fungal infections (ringworm), but use has fallen out of favor due to side effects, and availability of effective antifungal therapy with safer drugs such as itraconazole and terbinafine
Fulvicin, Gris-PEG
Dogs, cats and horses
Antifungal
Yes
Do not use in pregnant or lactating animals as griseofulvin is a potent teratogen. Pregnant women should avoid handling this drug.
Lack of appetite, vomiting, diarrhea, depression or weakness, bone marrow suppression causing neutropenia, especially in cats infected with feline leukemia or feline immunodeficiency viruses. Kittens are more susceptible to side effects.
Yes
Griseofulvin has been used in pets to help clear dermatophyte infections, often in conjunction with topical treatments. Use has fallen out of favor due to availability of safer effective medications. Griseofulvin can be toxic and should be used as directed to avoid any side effects. Do not administer to pregnant animals as this drug can be teratogenic. Pregnant women should wear gloves to administer. Avoid use in cats infected with FeLV/FIV.
Ringworm (dermatophyte) infection; however, griseofulvin use is falling out of favor as more effective anti-fungal medications with fewer side effects such as terbinafine and itraconazole are now available.
Griseofulvin prevents fungal organisms from replicating.
Dogs and Cats: 5-10 milligrams per kilogram ultramicrosize griseofulvin given orally once daily; 25mg/kg day microsize griseofulvin orally once a day with a high fat meal
125 and 250 mg tablets of ultramicrosize griseofulvin are available; 250 and 500 mg microsize tablets; 125mg/5ml liquid oral suspension; veterinary labeled tablets are not available commercially at this time .
Tablets should be stored in a cool, dry place.
It may take several weeks to see an improvement in skin lesions due to ringworm infection. Treatment should continue beyond the resolution of the lesions.
Consult your veterinarian if a dose is missed. This medication can be easily overdosed.
Overdose is possible, and the normal side effects are more severe with overdose.
May be more likely in kittens and include:
Do not use in:
Do not use with phenobarbital, cyclosporine or estrogen-containing medications.
Do not use in pregnant or lactating animals. Pregnant women should avoid handling this drug due to teratogenicity. Monitor CBC q 3 weeks during use.
There are no known laboratory considerations when using griseofulvin.
VIN Veterinary Drug Handbook
Disclaimer
The information contained on this page is for educational purposes only. This medication should only be given under the advice of a veterinarian who has examined your pet under the laws applicable to your state of residence.