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This represents a pretty substantial overdose. Corbett got about 2.5 times more than the highest published dose for pain relief. However, it's thought that buprenorphine has a high index of safety, and even large overdoses don't usually cause serious effects. I'm assuming you gave it on the gums ("transmucousally") as that's how it's typically prescribed for pain relief at home in cats. Because of that method of administration, there's no way to remove the drug from his system by inducing vomiting. There is a reversal agent that is somewhat effective, but may have to be given in multiple doses due to the way buprenorphine works. The drug is naloxone, and your veterinarian should have this drug. Because the signs of overdose can be concerning (vocalization, ataxia, hypersalivation, decreased body temperature, and lethargy) my best recommendation would be for you to take Corbett back to your veterinarian for administration of this drug, so that the overdosage can be averted.

Hello. No, it is not. Omeprazole is commonly known as Prilosec, & it is used to decrease stomach acid production, & is useful for GI ulceration & bleeding. This would certainly make someone feel better, but it is not actual pain medication. Thanks for using Petco Pet Education Center, formerly Petcoach.

I am worried about poor Quincy. You're right to think that Simbadol is for cats, it's a high dose, longer acting version of buprenorphine, an opiate pain reliever. Buprenorphine is also used "off label" but the regular strength variety is usually safe in dogs. All opiates can potentially make a sick or debilitated dog worse, per the veterinary formulary, so using a lower dose in old dogs is recommend. Speak to your vet about why they chose Simbadol, and your concerns that he seems to have deteriorated. I know your vet would not have wished to cause him harm, and I'm sure intended for Quincy to be more comfortable.

Ask your veterinarian to write a prescription for the generic form of Buprenex which is buprenorphine. Contact local pharmacies in big stores (WalMart Target, Costco, etc) that may offer more affordable pricing. Other options include Wedgewood Pharmacy ( https://www.wedgewoodpharmacy.com/ ) or Diamondback Drugs ( http://www.diamondbackdrugs.com/ ). These are compounding pharmacies. Discuss other options with your veterinarian. He or she may have a preferred vendor or different options than the ones above.

Hi there and thanks for posting on Petco Pet Education Center, formerly Petcoach! Phenoleptil is phenobarbital which is commonly used to help prevent seizure activity in dogs. Non steroidal anti-inflammatory drugs can be used such as Previcox (Firocoxib) or Deramaxx (Deracoxib). Rimadyl (Carprofen) should be avoided due to increased risk of liver toxicity. Opioid medications such as Tramadol are used with caution as these can cause increased sedation while on phenobarbital in some pets. Depending on what the cause of the pain may be, a drug such as Gabapentin which is typically used to neuropathic pain, may be a safe option. I hope this helps!

Tramadol has been found to have very little effectiveness in pain control in dogs. So less and less vets are prescribing it. Of course humans are abusing it, and it is a controlled drug. But the main reason is that it just is not that effective. Here is a research article: https://avmajournals.avma.org/doi/pdfplus/10.2460/javma.252.4.427?utm_content=buffera3998&utm_medium=social&utm_source=facebook.com&utm_campaign=buffer

It depends which kind of opioids, some of them can depress the breathing and are contraindicated with respiratory problems. Normally they are used at very small doses just to tip the edge of anxiety off in pneumonia patients and they would not cause such a serious consequence as death on their own.