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Budesonide is a glucocorticoid used in the treatment of inflammatory intestinal diseases in dogs and cats.
Inflammatory intestinal diseases
Entocort EC, Uceris
Dogs and cats
Immuno-suppressive
No
Not safe for use in pregnant or lactating animals.
Increased thirst/urination, increased appetite, decreased activity, muscle weakness, panting
Budesonide is a glucocorticoid with limited systemic effects. It is most often used in dogs and cats that are not responding to or are intolerant of systemic steroids.
Budesonide is used in the treatment of inflammatory intestinal diseases.
Budesonide has excellent topical activity. By delaying dissolution of the capsule until it reaches the duodenum (a part of the intestines), the drug can exert its topical anti-inflammatory effects in the intestines.
Dogs: 1-3 milligrams by mouth every 24 hours.
Cats: 1 milligram by mouth every 24 hours.
The medication dosages listed represent the variation in dosing for all underlying medical conditions. Medications should only be administered to pets under the direct guidance of a veterinarian.
Budesonide extended-release capsules for oral use come in 3 and 9 milligrams. Budesonide may need to be compounded into dosage strengths that are suitable for cats and dogs.
Budesonide oral capsules should be stored at room temperature (59-86 degrees Fahrenheit).
Pet parents can expect an improvement in their pet’s intestinal inflammatory disease.
If a dose is missed, continue with the next dose at the scheduled time.
Overdoses are rare and usually are not of concern. In cases of massive overdose, decontamination is recommended.
Budesonide can cause:
*Avoid use in pets with a previous sensitivity to budesonide
Drugs that inhibit the CYP3A enzyme can increase the amount of budesonide that enters the circulation.
Examples include:
Oral antacids should not be given at the same time as budesonide; they may affect the pH of the stomach and dissolution of the drug’s coating is pH dependent.
Budesonide should be used with caution in animals with gastrointestinal ulcers, active infections, diabetes mellitus or cataracts.
Plumb’s Veterinary Drug Handbook
Disclaimer
The information contained on this page is for educational purposes only. This medication should only be given under the advice of a veterinarian who has examined your pet under the laws applicable to your state of residence.