My dog has Cushing's & heart issues. Terbutaline dose & crushing?

Vetoryl (trilostane) is the best medication for managing Cushing's disease, but I'm sorry to hear that Lacy has not been tolerating it well. I have anecdotally heard of some vets using a variety of supplements for managing Cushing's disease signs, but these supplements will not ultimately decrease the cortisol production by the adrenal glands and generally seem ineffective. I don't know how long Lacy was receiving Vetoryl, but some dogs can initially become lethargic, vomit, have diarrhea, or a decreased appetite. Fortunately, these signs typically resolve after a few days to a few weeks on the medication. It may be worth discussing a temporary dose adjustment with Lacy's vet to see if she tolerates a lower dose better before gradually increasing to her 30mg dose. Some dogs also benefit from supportive measures (anti nausea medications, bland diets, etc.) in the first few days to weeks of treatment. I hope this helps and that all goes well!

Hello and thank you for contacting Petco Pet Education Center, formerly Petcoach. I will strongly discourage you from giving Sophia Trilostan without knowing for sure that she has Cushing disease. She may have, for example ascites, diabetes or internal organ enlargement, which makes the belly look potted. In that case, giving Trilostan can lead to a life-threatening hypoadrenal crisis. Please, take your dog to your local vets to confirm the diagnosis and then start the treatment, if necessary.

Hi there! You are correct that Cushing's disease would be a common cause of the symptoms you are describing in an older dog (excessive panting, weight gain, and drinking/urinating more than normal) - however, there are also other illnesses that could cause this, so diagnostic testing would be needed as a first step to find out if Cushing's disease is even the problem or not. It would be EXTREMELY unsafe to start Vetoryl or any other medication for this condition without even knowing for sure if Tily has it, since these meds would be very dangerous for a dog to take if they weren't needed, and close monitoring of cortisol levels is needed for dogs who are on medication for Cushing's disease because if the dosing isn't right they can get very sick or even die. So this would be a problem that you would need to work closely with your veterinarian to diagnose and treat safely - it's not something you can do yourself at home, just based on guessing. If taking Tily to the vet is difficult for you, I would suggest calling around to some local clinics to see if there is anyone in your area who does house call visits. A mobile veterinarian could examine Tily and take the required lab samples (usually blood and urine testing, as a starting point), and then go from there depending on what is found.

It's never a good idea to stop or make any dosing changes in a prescription medication without your vet's input, so I would definitely recommend giving him/her a call to discuss your concerns before you change anything. In general, I can tell you that if your dog has symptoms like lethargy, vomiting or diarrhea, or not wanting to eat, this may be a sign that the trilostane dose needs to be reduced. So this is definitely cause for concern - I would call your vet today to let them know. They may recommend having Max come in for blood work to check his cortisol levels - this will help determine what needs to be done regarding his medication.

Hello there! Thank you for using Petco Pet Education Center, formerly Petcoach to post your questions regarding Maxx. It looks like he is on quite the combination of medications to try and suppress the coughing. I personally do not find that the cough tabs help much. I have had great success using hydrocodone or butorphanol tablets. The albuterol is good for a bronchodilator. You might consider talking to your veterinarian about using a inhaler called flovent. Fluticasone might be a better option to use. I would talk to your veterinarian about these other options and see if this would work best for Maxx. Please feel free to contact me if you have any other questions or concerns. I am also available to talk with via text or phone using the consultation service

I am very sorry that Yager is so ill. Unfortunately Cushing's disease is a progressive disease and cannot be healed. There are two possible causes for Cushing's: 1) a pituitary tumor (a tumor in the brain) that is telling the adrenal glands to make more cortisone that the body needs and 2) a possible adrenal tumor that is overproducing cortisone. Most of the time the cause is a pituitary tumor. Unfortunately the medicine your dog is taking is only affecting the adrenal glands, ie basically reducing cortisone production. In the meantime the tumor in the brain keeps growing slowly, Sometimes the medicine works too well and the body is not getting enough cortisone because the adrenal glands are not producing enough anymore (the medicine destroyed too much tissue). This can cause the signs you describe and therefore your vet recommends that you halve the dose. The other problem is that your dog's tumor is growing and may be pressing on vital structures in the brain now, which can cause seizures, wobbly gait, fainting spells. So I suggest that you trust your vet and follow his recommendations. Unfortunately the day will come that you need to say good bye to Yager when the tumor is causing too many problems. Listen to your dog: he will tell you when it is time.

Hello. For the most part, Vetoryl is used to control the symptoms of Cushing's by controlling the production of glucocorticoids. Overproduction of glucocorticoids is responsible for the symptoms of excessive drinking & urination but does nothing for the actual tumor growing on his pituitary gland. If Izzy's symptoms are manageable & tolerable then medication is not necessary. This would be your choice. But if his symptoms do get worse, at least consider once a day dosing. Most dogs do very well on twice daily dosing, but once a day can help in many pets. Thanks for using Petco Pet Education Center, formerly Petcoach.