My Great Dane swallowed diclofenac. Is this dangerous for my dog?

Oh dear! This is a pretty significant overdose, and NSAIDs (non-steroidal anti-inflammatory drugs) like Previcox have a fairly narrow margin of safety in dogs. Overdoses like this can result in severe stomach ulcers, internal bleeding, or even kidney failure. Since she got such a large dose, I would really recommend taking her to the vet right away for treatment. He/she can give her an injection to induce vomiting to help get any remaining pills out of her stomach before they can be absorbed, and may also recommend giving her IV fluids and starting medication to help protect her stomach to try and prevent any problems.

As long as the smaller dog doesn't have any pre-existing liver or kidney issues, its unlikely that this will be a problem. Watch for vomiting, diarrhea, or decreased appetite, or lethargy; if you notice any of these symptoms, take him to the vet for an exam and bloodwork. Again, though, based on what you are describing, as long as Bean is otherwise healthy, I think its extremely unlikely that this will cause any issues. Thanks for asking Petco Pet Education Center, formerly Petcoach!

Thank you for contacting Petco Pet Education Center, formerly Petcoach with your question about Hudson. He should be ok. While Dexilant isn't a drug regularly used in veterinary medicine, I found information that states "According to toxicity studies there was no effect from the drug on dogs when given at a dose of 5mg per kilogram (2.2 pounds) of body weight for several days in a row." With his weight of 85 pounds, there will be no issues. Just do not give him anymore. I hope this helps!

While I would certainly recommend calling aspca poison control, I do not believe that 5mg of warfarin exceeds the threshold for a toxic dose based on a 6 kilogram body weight. According to the academy of vet pharmacists, a 5 mg per kg dose is the threshold meaning that about 30 mg is needed to show clinical signs in most cases. However every patient is different and if your dog has any other issues or takes other meds this could be affected. Hope this helps.

There is a chance that it will pass through with no problems, especially if it was a small piece of twine. Monitor her for vomiting and diarrhea and have her examined by your vet if you notice anything abnormal.

Considering that Naproxen has a very narrow safety margin and a maximum dose of 2mg/kg is described in literature, your dog would have received a seven-fold dose, ie 500mg /35kg = 14 mg/kg, thus making it likely that he may develop some stomach and kidney trouble. I would recommend that you call ASPCA's poison control number. That number is 888-426-4435. There is a $65 charge, but they will be able to best advise you. Please have the label available so you can let them know the amount of medication listed and what any other potentially concerning ingredients were.  I hope thats helpful, thanks for using Petco Pet Education Center, formerly Petcoach

This is likely not enough garlic to pose a serious risk of toxicity. At worst, you may see some mild stomach upset. Withhold food for 24 hours and feed a bland diet in small, frequent amount until symptoms resolve.