Dog skin blisters spreading: Is it mange or a severe skin infection?

Poor guy. I would highly recommend asking your vet to perform a skin scrape on Tombo. These lesions are suspicious for possible demodexx mites. The trumectin is a Demodexx treatment; however, you didn't mention that your vet actually tested for this. If this is a mite problem, then a topical medicated shampoo can be used in conjunction with the injections to gain better control of the overpopulation of mites on the skin. Also there are several other products that treat for mites that may be more effective for him, such as the off-label use of Nexgard, Bravecto or Simparica (have to be 6 months or older, so this may be an option depending on his exact birthdate). Also a skin culture should be done to determine which antibiotic will get rid of this infection for a certainty. Most skin infections will respond to broad spectrum antiobitcs, but there can be resistant infections that don't respond, which may be the case with your pet Tombo. This infection doesn't look particularly fungal in nature; however, if your vet already did a skin impression to confirm there is yeast present on the skin, then definitely continue with the Fluconazole treatment as prescribed. These viable tests (skin culture, skin scrape, impression) should give us a good idea on how we should be treating him from here moving forward. As a general rule of thumb, you can give you pet pet formulated fish oils for just about any skin condition in which the skin is red. Fish oils act as a natural anti-inflammatory and can also held with overall skin health. You can find these at your local pet store or through your vet office. I would also inquire with your vet about prescribing some antihistamines to help with any itching that Tombo has right now. That will help him allow his skin to heal and respond to all the treatments he is receiving. I hope this helps you find some resolve for Tombo's itchy/irritate and balding skin. Best wishes and take care!

I'm sorry to hear that Sasha has been licking and developing these skin lesions. Her lesions look most suspicious for a bacterial skin infection, but could also be a result of ringworm or mange. Personally, I never find Neosporin to be overly effective in managing skin infections. Instead, I prefer using medicated antimicrobial shampoos, particularly those that are chlorhexidine-based (here is one example: http://www.drsfostersmith.com/product/prod_display.cfm?pcatid=27982). Since Sasha is licking herself, consider also keeping an e-collar (cone) on her when she is not supervised (i.e. overnight or when you are out of the house) to prevent further irritation/damage to the skin. Be sure to take Sasha to her vet when they are back from vacation for further evaluation because many skin infections require oral antibiotics for resolution. I hope this helps and that all goes well!

Scrappy appears to have a very wide spread pyoderma (skin infection). This is most likely composed of bacteria and yeast. It is usually due to an underlying allergy and possibly a low thyroid level. Your vet can run lab work to check the thyroid level and correct that if needed. They do make medicine to help control allergies but she will need long term antibiotics with medicated baths to clear the infection. It typically is not contagious to other animals or people

Hot spots are small usually individual areas of superficial infection and tend to be moist and smell horrendous. Bathing and topical antiseptics are usually sufficient. Mange is an infestation of mites which crawl through the inner layers of the skin causing inflammation, itch and often hair loss, these damaged areas may then become infected with bacteria or yeast also. There are numerous mite treatments which can be effective from washes, spot ons and tablets; generally 3-months tresatment is required to eliminate the mites

Yes, this is most likely a bacterial skin infection. Usually oral antibiotics and some topical therapy (like medicated shampoo) will be prescribed. You will need to get those from your vet so I suggest you get Rolo in for an exam.

It looks as if your dog has a skin infection, most commonly caused by an allergy, a skin mite (Demodex) or fleas. 

The allergy could be a due to a protein in your dog’s food or an environmental allergy like to dust, pollens, grasses, etc. 

The allergy causes your dog to itch and chew at the skin which breaks down the skin barrier. This then leads to infection. Skin infections are typically characterized by large areas of hair loss, redness, crusting, flaking, and pustules. A thorough skin examination by your veterinarian should be able to determine the cause of the itch so it can be treated appropriately. Your dog will most likely need antibiotics to help clear up the infection and possibly an allergy/anti-itch medication like Apoquel, Atopica, or Cytopoint to give some relief while the infection clears up. A medicated shampoo may be beneficial as well. I would also recommend he be on a good flea control routinely too. Once the infection has resolved a long term allergy medication (like Apoquel or Cytopoint) can be given on a regular basis to prevent any future problems. I hope this helps. Thanks for using Petco Pet Education Center, formerly Petcoach. Best of luck.

This definitely looks like a skin infection and pretty deep. Unfortunately, topical over the counter medications are probably not going to be enough to clear this up. Dozer will need to see your veterinarian to get the right prescription antibiotic to treat this properly.