Which liver supplement is best for dogs: Canitone LS or Milk Thistle?

My best recommendation to supplement liver function is a supplement called Denamarin. It contains several of the known ingredients we historically used to support liver health all in one supplement. Very often, I observe my patients Liver enzymes decreasing dramatically on this supplement.

Dogs are typically given milk thistle in combination with Vitamin E, Zinc and s-adenosyl methionine for liver disease. The dose is usually lower when used with these other supplements. Doses ranging from 5 mg/kg to 50 mg/kg per day have been reported to likely be safe, so 400 mg twice daily would be within this dose range. I do not typically recommend giving this supplement unless there is evidence of underlying liver disease because it is not likely to be helpful. There does not seem to be evidence of kidney disease or other problems when milk thistle supplements are used long term in dogs, but there are no studies in dogs without liver disease. I would recommend checking with your veterinarian before starting this supplement since it can potentially cause problems when given in conjunction with some other medications.

Yes, a liver tonic such as zentonil can help support and allow the liver to repair. Mild elevation in liver enzymes are expected in young growing dogs but i would recommend monitoring in 2months or so to ensure they do not continue to increase

Hello, and thanks for using Petco Pet Education Center, formerly Petcoach. Yes, that product should be pretty safe. However, I don't recommend giving supplements such as this without being directed by a vet. The most important way to support Bruno's organ function is with a good high quality food, and good preventative care (disease prevention through vaccination, parasite control, etc). Milk thistle is a great liver support, but the other ingredients have limited data in dogs and, while probably safe, I would not recommend them.

slightly elevated ALT does not require immediate treatment, it could be an accidental finding especially if it is not significantly high. 1 pill once a day is enough and it cannot harm him in any way.

I am sorry to hear that Mello has not been well. If liver ultrasound is not conclusive, the best way to go forward is to take liver biopsy - this usually gives definite answer what is going on with the liver. Gall bladder stones are very rare in dogs but relatively easy to pick up during ultrasound scan. My advise would be to discuss liver biopsy with your vet. The supplement you bought is not going to hurt your dog, but at the same time it is very unlikely that it is going to help much if it is not used alongside proper diagnostics and other medical treatment.

Thanks for using Petco Pet Education Center, formerly Petcoach! There are several conditions that can cause an elevated ALP and some of them do not require therapy right away. However, in terms of supplements, you could consider using a product called Denamarin which can help the liver in general with several different conditions. Good luck and have a good night!