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Why is my dog lethargic and has diarrhea after his DA2PP shot?

Updated on September 23, 2025

Pet's info: Dog | Pit Bull Terrier | Male | unneutered | 21 lbs

after getting the DA2PP shot yesterday he is lethargic and had atleast one run of diarrhea. any suggestions

1 Answer

Most Helpful Answer

Jennifer Summerfield, DVM CPDT-KA

Answered By Jennifer Summerfield, DVM CPDT-KA

Veterinarian, Certified Dog Trainer

Published on March 22, 2017

Poor Kain! It's common for dogs to be a bit more lethargic than usual for a day or two after a vaccination - he might also act sore in the area where the shot was given. Sometimes loose stool can happen also. These are usually normal side effects that should resolve within 24-48 hours. If the problem continues longer than that, or if he has any vomiting, difficulty breathing, facial swelling, or if the diarrhea is bloody, I would recommend taking him back to your vet for a recheck visit since these can be signs of a more serious vaccine reaction.
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