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Do topical flea meds cause steroid responsive meningitis in pets?

Updated on September 23, 2025

This might be a weird question, but can topical flea meducation like advantix or frontline cause steroid responsive meningitis?

1 Answer

Most Helpful Answer

Destini R. Holloway, DVM

Answered By Destini R. Holloway, DVM

Veterinarian

Published on March 5, 2017

We believe steroid responsive meningitis is caused by an immune mediated disorder, but we aren't entirely sure, which is why it is an idiopathic disease (unknown cause). However there are no known documented cases of steroid responsive meningitis being caused by topical flea/tick medication. However, there are cases of seizure activity, muscle spasms, and skin irritation caused by either of these preventatives on rare occurrences.
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