Dog's chronic nose/eye fungus & leg lumps not responding to treatment?

It would depend on what type of mycosis Wendy has - there are many types of fungal infections that could affect the nose and some could spread to the eyes as well in which case oral medications might be necessary. Mycosis fungoides is a type of skin cancer, but I would think that oral chemotherapy would have been recommended if that was the original diagnosis. I would recommend rechecking with your veterinarian to see if they think the eye changes are related and what medications they would recommend.

Left nasal cavity seems full of discharge and bone seems affected as well (so whatever is inside is causing bone erosion as well). It is not possible to determine what it is specifically from the CT images and a further investigation is unfortunately needed. Was rhinoscopy performed? was a biopsy taken? Otherwise aggressive treatment for fungal infection is required (not only oral treatment but often ''flush'' of the nasal cavity is necessary to have substantial results. Hope this answer was helpful, but please do not hesitate to contact us again on the forum or by requesting a consultation if you have any more questions or to discuss it any further.

Based on previous diagnostics I would proceed with a biopsy ( a larger sample) as well as a culture and sensitivity. If there is growth on the sample, I would proceed with a longer duration of antibiotics as indicated. It may be worthwhile in the interim to start a low dose of steroids to reduce any inflammatory/allergic response, but I would only start after collecting a good biopsy and culture. This could be an infection, but it is also possible that it is a type of neoplasia like lymphoma or mast cell and a larger sample is likely needed to determine.

This is likely to be due to a fungal or bacterial infection. An immediate check up at your local vets would be necessary, combined with some skin testing (like hair plugs and culture) to confirm these suspicions. Hope this answer was helpful, but please do not hesitate to contact us again on the forum or by requesting a consultation if you have any more questions or to discuss it any further. If this answer was helpful please let us know, this will be used to improve our service!

I am sorry to hear about your dog. If this is not improving with topical medication he may need to be switched to oral/systemic medications as the problem may be deeper under the skin than topical meds can penetrate. I would let your vet know he is not improving. Occasionally we may need to do testing such as cultures or biopsy in some cases that don’t improve with traditional treatments.

I am concerned that Racer either has a reaction to something - like a spider or insect bite, or this could be a type of infection, possibly fungal like cryptococcus. I do recommend you take him in to see your vet tomorrow, they may suggest a needle biopsy to determine what is the cause, or possibly a blood test. I would expect they may suggest antibiotics to cover until results are back. It may be more apparent on physical exam as to the cause.

It's true that fungal infections can be a cause of nosebleeds in dogs, but they can also be caused by nasal tumors or even a foreign body such as a blade of grass or other plant material. Since there has been no improvement in four months with antifungals, I would be concerned that something else may be causing the bleeding. I would suggest having a rhinoscopy done to visualize the inside of the nasal cavity and take biopsies and culture samples of the tissue there to determine if the bleeding is really caused by a fungal infection or some other problem.