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Updated on September 23, 2025
Pet's info: Dog | Mixed Breed Large (61lb +) | Male | neutered | 1 year and 10 months old | 60 lbs
Hello,Last night my dog ingested 8 pills of mesulid 100mg. I’m not sure if he ingested them by himself because we have 3 dogs. He seems normal... How long should I monitor him for side effects?
2 Answers

Answered By Linda G, MS, DVM
Veterinarian
Published on April 26, 2019
Answered By Destini R. Holloway, DVM
Veterinarian
Oh no. That was naughty. Unfortunately this medication Mesulid is not tested in pets, but b/c it is an NSAID, I would highly recommend taking Smoke in to your vet for immediate evaluation. NSAID toxicity can take up to 48 hrs to manifest, and this is a big dosage, even if it was spread out amongst all 3 dogs. Symptoms of NSAID toxicity include excessive vomiting +/- blood, diarrhea +/- blood, lethargy and lack of appetite.
The vet likely will recommend bloodwork to evaluate the liver enzymes and then prescribe medication to help protect his GI tract as well as reduce further reabsorption of the drug. I hope that your pets turn out ok moving forward. Best wishes and take care!
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