Why is my cat phantom spraying and showing hyperesthesia signs?

So sorry that she is having this problem. If your vet has ruled out medical reasons and you have already tried pheromones, litter attractants, etc. then you could talk to your vet about trying an anti-anxiety medication, like Prozac, and see if that helps stop her from urinating inappropriately.

Hyperesthesia is basically where the pet has short bouts of excessive itch, that causes them to become very sensitive to touch, sounds, and any interaction really. It causes the pet to act in an exaggerated way which can include biting, tail chasing, and errotic unexplained behavior. Here is more information on the condition in detail --->https://veterinarypartner.vin.com/default.aspx?pid=19239&id=4952886 Treatment for this involves prescription anti-itch (i.e. Gabapentin) and/or anxiety medication that your vet will have to fill. There aren't any over the counter options for cats that can treat this condition successfully currently. I hope that your pet Pistol gets this treated soon, if she does indeed have hyperesthesia. Best of luck and take care.

Do flea control, if you have not done so yet. Even indoor cats can catch a flea brought in from the ourside. If there is no flea problem then your kitty may be suffering fom Feline Hyperesthesia Syndrome, which is a type of seizure disorder. I suggest you take her to your vet ASAP for an exam. There are mesications available to reduce these attacks, such as anti-anxiety medications. However, your vet needs to rule out other diseases that could cause sudden pain.

I generally recommend Feliway as a calming pheromone collar or diffuser as a first line of defense. However, female cats rarely "spray or mark" with urine. Tia may be developing a urinary tract infection, bladder stones or crystals in the urine as a result of the stress from your recent move and new friends. Her increased vocalization could be a result of either stress or pain from a UTI. It is worth first taking a trip to the vet for an exam and urinalysis to assure that she does not have a medical issue causing her urinary issues. I hope that all goes well!

If your cat has been diagnosed with feline hyperesthesia syndrome, that could definitely be factoring into her resistance to having you pet her. I recommend scheduling a vet consult to have her examined - many hyperesthesia cats will improve on medication. I would start there, before concluding that her scratching/biting is purely behavioral. However, if you don't notice any change in her behavior with hyperesthesia treatment, then it's worth considering behavior interventions and stress management. https://www.vet.cornell.edu/departments-centers-and-institutes/cornell-feline-health-center/health-information/feline-health-topics/hyperesthesia-syndrome Hope this helps!

Have Sophie examined by your veterinarian. A sterile urine sample should be collected and submitted for urinalysis and culture. Blood work can assess major organ function, especially kidney function. Provide an additional litter box where she is urinating. Use a litterbox attractant to entice her back into the boxes. A pheromone product such as Feliway spray or plug in diffuser may decrease any anxiety.

Thank you for submitting your question regarding Alfie. I recommend that he sees a veterinarian since you have tried a lot of at home remedies without success. He may benefit from an antidepressant medication as this can help spraying in cats. It is important for the veterinarian to rule out a medical problem first though. Urine testing is usually necessary to look for evidence of inflammation, infection or bladder stones. I hope this information helps!