How to determine the cause of pet pancreatitis and enzyme deficiency?

Hi there and thank you for using Petco Pet Education Center, formerly Petcoach to address your concern. Just because a Lipase is elevated does not automatically indicate that a dog has pancreatitis. Serum lipase and even amylase can increase with multiple other causes, not just pancreatitis. This is why it is difficult to diagnose pancreatitis based on these levels alone. If Diesel is symptomatic for pancreatitis with these values, I would have additional testing performed to help confirm pancreatitis. I would even consider an abdominal ultrasound if possible. I hope this helps! Please let me know if you have any other questions or concerns and I would be more than happy to help you further.

Hi, thanks for using Petco Pet Education Center, formerly Petcoach! I would not give Binx any additional medications or supplements as medications can cause pancreatitis. The pancreas aids in digestion by releasing digestive enzymes in to the duodenum (first segment of the small intestine). It also makes and releases insulin. Pancreatitis means inflammation of the pancreas. The digestive enzymes that are normally excreted in to the small intestine are activated to early with in the pancreas, in a sense causing digestion of the pancreas. Pancreatitis can be caused from medications, obesity, high fat foods or getting in to high fat foods and underlying diseases can be a risk factor. I hope this helps!

Pancreatitis is difficult to diagnose and is done by analyzing compatible clinical signs and lab test results. Cats with pancreatitis commonly experience lethargy, loss of appetite and occasionally vomit, but these clinical signs can also be caused by a variety of other conditions. Typical blood testing includes a CBC (red & white blood cell count and platelets), chemistry (to evaluate overall organ function, blood glucose and electrolytes), T4 (thyroid hormone), as well as a urinalysis (to evaluate kidney function and look for infection). If pancreatitis is still suspected, a blood test called an fPL can be done to either rule pancreatitis out or make you more suspicious of that as the diagnosis (this is not a conclusive test). Abdominal ultrasounds can be helpful to determine if the pancreas is inflamed or if other abnormalities are present, but these are not performed in all cases. Cats with pancreatitis commonly also have concurrent diseases - such as inflammatory bowel disease, cholangitis (inflammation of the gallbladder) or cholangiohepatitis (inflammation of the gallbladder and liver). Uncommonly, cats with pancreatitis can become diabetic if there is enough damage to the endocrine portion of the pancreas. There is no definitive treatment for pancreatitis. The goal is to manage Bella's clinical signs supportively (i.e. IV fluids, anti nausea medications, pain medications, etc.) as needed. If you are concerned about the treatment plan that your vet has started for Bella, call her to discuss the options. Odds are that she has a reason for starting or not starting certain medications or diagnostics. If you feel uncomfortable with this plan after speaking with her, it is always reasonable to get another opinion. I hope that Bella is feeling better soon!

Hi, thanks for using Petco Pet Education Center, formerly Petcoach! I am sorry that Angel has been so sick! Usually the need for pancreatic enzyme supplementation is based on blood work. Usually the TLI (a pancreatic enzyme) is low. Pancreatic enzyme are used to treat exocrine pancreatic insufficiency. Which can result from chronic pancreatitis as can Diabetes. Use in dogs and cats is considered off label, so you would have to discuss the use in Angel with a Vet that has examined her. Cats reportedly hate the taste but may accept the powder if mixed with fish/tuna oil and then thoroughly mixed with a canned food. If using solid dosage forms (enteric-coated tablets or compounded capsules made from powder or crushed tablets) be certain that immediately after dosing, water or food is consumed to reduce the risk for esophageal damage. You may also want to consider a probiotic, like Purina Fortiflora. I hope this helps and I wish you and Angel the best!

Feeding him before blood tests is not ideal and can really influence tests results (especially if it is a snap test for pancreatitis). I would recommend to repeat the test with a quantitative one if possible before getting into hospitalisation and treatment which may not be needed.

Pancreatitis is a "spectrum disease" meaning that inflammation of the pancrease, which leads to high levels, can cause anywhere from no clinical signs to severe life threatening signs. We treat symptomatically, so if he is having no signs I would just leave him alone and give his normal diet. You can recheck the values in 2-3 weeks to see if they have come down. Good luck with Jeter.

Thank you for submitting your question regarding Rocky. Lipase values can be elevated in cases of pancreatitis and occasionally liver and kidney disease. However, it is a not a very sensitive marker of this disease. For this reason, if the remainder of his blood work is normal and he is not acting sick, then I do not worry too much about an elevation in lipase. I hope this information helps!