Why are both my cats sick with mouth pain and scratching for weeks?

Ouch, that must be very painful to Frankee and the kitten. There are a couple of reasons why they may have both developed these ulcers, and they include nutritional (protein - calorie malnutrition, riboflavin deficiency), infection (FeLV, FIV, calicivirus, herpes virus), toxins, foreign body, or electric cord shock. I would take them both into the vet first thing in the morning for an exam, as it's concerning that they are both showing the same symptoms. It will also be painful for them to eat, and cats should not go long without eating or they end up at risk of developing a fatty liver. The vet can do a physical exam, blood tests, a urinalysis, and any other tests they deem necessary. Once a cause is found, the vet can discuss treatment with you. I would offer them both gently warmed wet food tonight to tempt them to eat.

I would get him in as soon as you can, but not necessarily as an emergency. It could probably wait until Monday. There good be an infected tooth, inflammation in the gums, a small ulcer or mass, or something else causing this behavior.

There are some contagious viruses such as calicivirus that can cause ulcers in the mouth along with other upper respiratory signs such as sneezing and nasal discharge. It is also possible that both cats were exposed to a toxin or something caustic that injured their mouths if they go outdoors or have access to any chemicals. If their symptoms have been present for more than 24 hours I'd recommend taking them to an emergency veterinarian. They can examine both cat's mouths to look for problems and determine whether or not they may be dehydrated from not eating or drinking.

If you see one flea, there could be many more. I would recommend that Alice be on year-round flea prevention for this issue. What you describe could be an eosinophilic granuloma. I recommend that Alice get checked out by a vet to confirm this possibility, or to see what else could be causing it. These granulomas can certainly flare up with inflammation or allergies, which would be caused by fleas. Other possible causes of itching include mites, ringworm, or other allergies. Here is some more information about eosinophilic granulomas: http://www.veterinarypartner.com/Content.plx?P=A&S=0&C=0&A=656

It could be Wednesday keeps scratching at it or rubbing her face preventing it from healing. I'm also concerned it could be infected. I'd have her seen by a vet this weekend to have this treated so it can finally heal. I hope this helps!

I'm sorry the babies aren't doing well. With some feline viral diseases they can develop ulcers in the mouth that can be painful. Make sure to follow up with their vet tomorrow and discuss this as well as any test results. With such young babies illness can easily be fatal but supportive care and feeding if their best chance. In some cases tube feeding and medication via a tube may be needed but please don't attempt without being shown how by your vet clinic. Good luck with them and thank you for giving them a chance.

The cat pulling out fur could have fleas, allergies, skin infection, mites, etc. He should be examined by a vet to determine the cause and best treatment. He may need an antibiotic, anti-histamine, corticosteroid, or other medications. Your other cat may have an upper respiratory infection and/or eye infection. She should also be seen by a vet for treatment as she may need an antibiotic and eye drops. Please have your vet take a look at both of them so treatment can be started.