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What are the best treatment options for a cat with acromegaly?

Updated on September 23, 2025

Pet's info: Cat | Mixed Breed | Male | neutered | 10 years and 1 month old

Oscar has been diagnosed with a acromegaly tumour in the petriliy gland recently however out vet isnt 100% sure what we can do to make him most comfortable and when so we are asking diffrent vets opinions

1 Answer

Most Helpful Answer

Linda G,  MS, DVM

Answered By Linda G, MS, DVM

Veterinarian

Published on March 27, 2018

Hello. First, I assume you mean the Pituitary Gland instead of petriliy gland.
Second, most of these cats are diabetic. I assume yours is too.
From a Veterinary Information Network paper last updated in 2018, here are the current recommendations for treatment/management.
1. Somatostatin analogues. Somatostatin is a hormone secreted by the hypothalamus that works on the pituitary gland to decrease the secretion of Growth Hormone (GH). Octreotide is one & a newer Pasireotide has shown promise.
2. Radiation Therapy has been widely used to treat feline acromegaly.
3. Hypophysectomy, surgical removal of the pituitary gland is an option but requires a very skilled surgeon.
4. Supportive therapy for the cat where the acromegaly cannot be addressed directly. Here, higher doses of insulin can be administered to achieve better glycemic control & decrease the outward signs of diabetes. While this can make the symptoms better for your cat, it does not address the underlying disease.
Here in the US, hypophysectomy is a promising treatment modality but is not widely available, and the newer somatostatin analog is also showing great promise. Thanks for using Petco Pet Education Center, formerly Petcoach.
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