Best* Dewormer for Dogs of 2022

When your dog is infested with parasites, you want them gone—fast. Petco has some of the best dewormers for dogs, at all different price points.


Pet parent faves

When your pup isn’t feeling well, all you want is to make them feel better so they can be their loving goofy selves again. The best dewormers for dogs work quickly and efficiently. These best-sellers are the solutions our pet parents reach for the most when seeking relief for their pup.

Bayer Quad Dewormer Tablets for Dogs


Quad Dewormer Tablets for Dogs

Bayer is a trusted brand for both humans and canines. These chewable tablets will help remove tapeworms, whipworms, hookworms and roundworms from your dog’s digestive tract, bringing them relief.

  • Contains two tablets for medium-sized dogs who weigh between 26-60 lbs.
  • Broad-spectrum medicine is effective against 4 types of parasitic worms
  • Convenient chewable tablets can be fed to dogs directly or mixed in food

Sentry Grain Free Tundra Premium High Protein Fresh & Raw Animal Ingredients Dry Cat Food


HC Wormx Plus Flavored Dewormer Chewables for Dogs

These broad-spectrum tablets by Sentry tackle two different species of roundworms, 3 different species of hookworms, and are an effective tapeworm dewormer for dogs. The chewable tablets are also flavored, which may make dispensing the medication easier for both you and your pet—they’ll just think they’re getting a treat.

  • Available in 2-count or 6-count blister packs
  • For medium and large dogs who weigh more than 25 lbs.
  • Treats 7 different species of canine parasital worms

Simparica Trio Chewables for Dogs

Simparica Trio

Chewables for Dogs

The Simparica Trio helps prevent 5 different parasites that can plague your pup—roundworms, hookworms, heartworm, fleas and 5 different species of ticks. All these parasites have the potential to make your dog seriously ill. Simply give this chewable tablet to your dog monthly to help prevent infestations from occurring. Their meaty liver flavor may even encourage your pup to be excited about their monthly dose.

  • Available in 6-treatment packs
  • Suitable for puppies and dogs 8 weeks or older, weighing between 44.1-88.0 lbs.
  • 6-month supply
  • Available via prescription only

Pet Armor 7-Way Chewable Dewormer For Puppies and Small Dogs

Pet Armor

7-Way Chewable Dewormer For Puppies and Small Dogs

These dewormer pills for dogs are designed for small dogs and puppies. They defend against roundworm, tapeworm and hookworms, and are flavored to be more palatable for your pup. They’re also conveniently chewable. Simply follow the weight chart on the back of the package.

  • Available in 6-count blister packs
  • For puppies and small dogs who weigh between 6-25 lbs.
  • Flavored chewable

Pet Armor 7-way Chewable Dewormer

Pet Armor

7-way Chewable Dewormer

Pet Armor’s 7-way dewormer for dogs isn’t just for the small pups—it’s available for our large canines as well. Just like its smaller dog counterpart, the chewable tablet is flavored for easier administration and gives your best friend protection against roundworms, tapeworms and hookworms.

  • Available in 6-count packs
  • For medium to large dogs weighing between 25.1-200 lbs.
  • Can be dispensed with or without food

Trifexis Chewable Tablets For Dogs


Chewable Tablets For Dogs

If you want a one-and-done monthly tablet to prevent the majority of parasites your dog can contract, Trifexis is what you’re looking for. It protects your pup against whipworms, roundworms, hookworms, fleas and heartworm. It is a prescription dewormer for dogs, so simply consult your vet and have them call it in to your Petco pharmacy. They’ll ship it conveniently to your door.

  • Available in 6-count packs
  • For medium to large dogs weighing between 25.1-200 lbs.
  • Can be dispensed with or without food

Drontal Plus Chewable Tablet

Drontal Plus

Chewable Tablet

This is another prescription dewormer for dogs. It helps to kill hookworms, whipworms, tapeworms and roundworms. This treatment can be used on dogs that are over 2 lbs. and puppies that are at least three weeks old.

  • Available in 1-tablet or 2-tablet packs
  • Available via prescription only
  • Can be used for puppies as young as 3 weeks old

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Learn More About Dewormers for Dogs

The best medication to treat your dog’s parasites depends on what type of infestation your dog has contracted. The 5 common types of worms are:

  • Heartworm
  • Whipworm
  • Roundworm
  • Tapeworm
  • Hookworm

They vary in severity, and all are contagious—some can even be passed to humans. Make sure you always protect yourself accordingly if your dog has worms. Their eggs can survive for a very long time—sometimes even years.

A common way they get transmitted is through an infected dog’s feces. Even if the stool is picked up and discarded, the microscopic eggs can live in the dirt. Dog parents know that canines love to smell and taste everything—all it takes is a quick sniff or lick of infected soil, or your dog getting the offending eggs stuck to their paws and licking them afterwards.

Your canine can also get worms from other parasites like fleas or mosquitos. They can also get them from rodents. Worms can also be transmitted to puppies if the mom is infected via the milk.

When seeking the ideal dewormer for dogs, consult your vet for a diagnosis of what type of worms your dog has. There are many broad-spectrum dewormers that get rid of numerous species, as well as natural dewormers for dogs. But you won’t know which to choose if you don’t know what kind of worm it is. It’s also important to be as accurate as you can on the dosage, so your vet can weigh your pet and help you determine the correct amount to give.

That all depends on the the age and size of the canine, and the severity of the infestation. Your vet may prescribe a liquid dewormer for dogs, or one that comes in a tablet or a paste. Your vet might also recommend an over-the-counter medication. .

After a worm infestation, your pup may be lacking nutrients, or may have developed a bacterial imbalance in their belly. Consult your vet about probiotics, stool softeners and enzymes for dogs to see if they recommend putting your pup on a supplement regimen.

Since worms can be transmitted so easily, it’s best to have your dog on a preventive medication all year round, and to get their stool tested for parasites during their annual checkup.

Often, you can’t detect worms with the naked eye. That means if your dog developed an infestation, they may not have symptoms until it is too late. Some worms—like heartworms—can be fatal. It’s best to take steps to prevent your dog from ever getting them the first place.

Talk to your dog’s vet about which preventive they recommend. Combination treatments that prevent fleas, worms and ticks are very convenient—they only need one dose a month. Your vet can prescribe you the best preventive to suit your dog’s needs.

If you need a vet, check out your neighborhood Petco Pet Center. Many offer veterinarian services located right in the store. Simply hop online and make an appointment. 

Are you a new pet parent? Our Petco Resource Center can help. Our New Dog Owner Guide can help fill you in on the basics, and our Dog Care Sheet provides you with even more essential information about your new best friend.

*Based on sales data.