For FRONTLINE Gold, remove one applicator tube from the packaging and hold it in an upright position pointed away from your face. Twist the dispensing tip clockwise about ½ turn while pushing down to break the tube's seal. Do not remove the dispensing tip. Before applying, make sure your pet is dry and can remain dry for 48 hours after application. Position the dispensing tip on your pet’s back between shoulder blades. Use the dispensing tip to part your pet’s hair so that the product will be applied at skin level. Begin squeezing out the contents of the tube to form a stripe as you move from shoulder blades down along your pet’s back to the base of their tail. Do not bathe your pet within 48 hours of application.
For FRONTLINE Shield, remove the applicator from the packaging and hold the tube upright away from you and your dog’s face. Cut the applicator tip with scissors to open, then apply the entire contents of the applicator directly onto your pet’s skin in 1 to 4 sites—this changes according to your pet’s size, so read the label for full instructions before use—squeezing the applicator until empty. Ensure that FRONTLINE Shield for Dogs is not applied superficially on dog's hair.