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$34.84 - $115.99

15% Off Frontline Plus & Shield

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FRONTLINE Flea and Tick Treatment

For decades, FRONTLINE has led the charge against fleas and ticks, delivering vet-trusted, pet-tested, fast-acting, long-lasting topical treatments that stop fleas and tick infestations cold. Since every pet is different, FRONTLINE offers a diverse lineup of products to meet the unique lifestyle needs—and parasitic threats—facing your pet.

FAQs About FRONTLINE Flea and Tick Treatment

FRONTLINE brand products provide pet parents with easy, effective, topical flea and tick treatments from a global leader in parasite protection. FRONTLINE Plus, FRONTLINE Shield and FRONTLINE Gold all contain active ingredients that target both adult fleas and ticks, as well as flea eggs and larvae to break the flea life cycle for good.

For FRONTLINE Gold, remove one applicator tube from the packaging and hold it in an upright position pointed away from your face. Twist the dispensing tip clockwise about ½ turn while pushing down to break the tube's seal. Do not remove the dispensing tip. Before applying, make sure your pet is dry and can remain dry for 48 hours after application. Position the dispensing tip on your pet’s back between shoulder blades. Use the dispensing tip to part your pet’s hair so that the product will be applied at skin level. Begin squeezing out the contents of the tube to form a stripe as you move from shoulder blades down along your pet’s back to the base of their tail. Do not bathe your pet within 48 hours of application.

For FRONTLINE Shield, remove the applicator from the packaging and hold the tube upright away from you and your dog’s face. Cut the applicator tip with scissors to open, then apply the entire contents of the applicator directly onto your pet’s skin in 1 to 4 sites—this changes according to your pet’s size, so read the label for full instructions before use—squeezing the applicator until empty. Ensure that FRONTLINE Shield for Dogs is not applied superficially on dog's hair.

No prescription is required, so you can browse Petco’s selection of FRONTLINE treatments for cats and dogs online and place your order at, or shop at your neighborhood Petco Pet Care Center.

To apply FRONTLINE Plus, simply remove the applicator from its blister packaging, then hold the tube upright with foil side toward you and snap the applicator tip. Part your pet’s hair between shoulder blades and place the applicator tip just above the skin, then squeeze. Apply the entire contents of the applicator in a single spot directly onto your pet’s skin. Avoid contact with the treated area until dry.

FRONTLINE Plus contains the active ingredients fipronil, which is used in the treatment of fleas, ticks and chewing lice, and the insect growth regulator (S)-methoprene, which kills flea eggs and flea larvae, as well.

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