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Comfortis: Chewable Flea & Tick Treatment

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Frequently Asked Questions

Comfortis is a monthly chewable tablet used to kill fleas and indicated for the prevention and treatment of flea infestations in dogs and cats. Its beef flavor is derived from pork protein and hydrolyzed soy.

Comfortis is for dogs 14 weeks of age and older, and 3.3 lbs of body weight or greater.

Comfortis is for cats 14 weeks of age and older, and 2 lbs of body weight or greater.

  • Comfortis comes in a convenient, beef-flavored chewable

  • Starts to kill fleas within 30 minutes and protection lasts an entire month

  • Spinosad, the active ingredient in Comfortis, is environmentally friendly

The active ingredient in Comfortis, spinosad, works on the nervous system of a flea, causing paralysis and death.

Comfortis is a chewable tablet that is given orally with food for maximum effectiveness. If vomiting occurs within one hour of administration, redose with another full dose.

Comfortis is preferably started one month before fleas become active and should be given monthly through the end of the flea season. In areas where fleas are common year-round, monthly treatment should continue the entire year without interruption.

This medication should only be given to the pet for whom it was prescribed.

Cats: Comfortis kills fleas and is indicated for the prevention and treatment of flea infestations (Ctenocephalides felis), for one month, on cats and kittens 14 weeks of age and older and 4.1 pounds of body weight or greater.

Dogs: Comfortis kills fleas and is indicated for the prevention and treatment of flea infestations (Ctenocephalides felis), for one month, on dogs and puppies 14 weeks of age and older and 5 pounds of body weight or greater.

For Cats: The most common adverse reaction recorded in clinical trials was vomiting. Other adverse reactions were: lethargy, decreased appetite, weight loss, and diarrhea. Use in caution with concomitant extra-label use of ivermectin. The safe use of Comfortis in breeding, pregnant, or lactating cats has not been evaluated. Please see product label here.

For Dogs: The most common adverse reaction reported was vomiting. Other adverse reactions reported in decreasing order of frequency are: depression/lethargy, decreased appetite, incoordination, diarrhea, itching, trembling, excessive salivation and seizures.

Comfortis will start to kill fleas within 30 minutes and it should remain effective for one month. If the pet was already infested with fleas when Comfortis was given, you may see fleas after that period of time as the immature forms of the fleas in the environment hatch.

Comfortis comes in a chewable tablet form.

Comfortis

KUM-FOR-tiss

Spinosad

If fleas are already present, discuss what other flea control measures should be used. Talk about what flea products to use on any other pets in the household, since all pets should be treated if there is an infestation. Have your veterinarian explain the life cycle of the flea and how that influences the effectiveness of monthly flea products.

Tell your veterinarian if your pet has epilepsy, could be pregnant, or is currently taking the medication ivermectin.

Notify your veterinarian of any other medications or supplements your pet is taking, and also if your pet has had any reactions to previous medications.

If you miss a dose, give it as soon as you remember and resume giving it every 30 days (once a month).

If a flea infestation is present, all pets in the household should be treated with an appropriate product. You may see fleas on the pet after giving Comfortis. The fleas will need to be on the pet to have contact with the Comfortis that will kill them.

Not for use in animals hypersensitive (allergic) to spinosad. Use with caution in breeding, pregnant or lactating animals (female animals nursing their young). Spinosad enters the mother's milk. Consult your veterinarian before using spinosad in a lactating dog or cat. The safe use of Comfortis in breeding males has not been evaluated.

Do not use in dogs less than 14 weeks of age or less than 3.3 lbs of body weight.

Do not use in cats less than 14 weeks of age or less than 2 lbs of body weight.

Consult your veterinarian before using in animals on high doses of ivermectin.

Use with caution in dogs or cats with pre-existing epilepsy.

Side effects are rare at the recommended dosage. May see vomiting, decreased appetite, lethargy, diarrhea, cough, excessive thirst, vocalization, increased appetite, redness of skin, hyperactivity or excessive salivation. Consult your veterinarian if you notice any of the above side effects.

If your pet experiences an allergic reaction to the medication, signs may include facial swelling, hives, scratching, sudden onset of diarrhea, vomiting, shock, seizures, pale gums, cold limbs, or coma. If you observe any of these signs, contact your veterinarian immediately.

Store at room temperature. Keep out of reach of children and pets.

If you know or suspect your pet has had an overdose, or if you observe any of the side effects in your pet, contact your veterinarian immediately.

Do not use in animals that are receiving high doses of ivermectin, as ivermectin toxicity may occur.