1 - 1 of 1 results
Available For Pickup At :


Frequently Asked Questions

Anipryl is a medication used to treat cognitive dysfunction and senility in older animals.

Anipryl is for dogs.

  • Used to treat clinical signs of Canine Cognitive Dysfunction Syndrome

  • Only FDA-approved drug for canine senility

  • Used for some types of Cushing's disease caused by a pituitary tumor in dogs

  • Approximately 70% of dogs with cognitive dysfunction respond to this medication after one month of treatment

Anipryl increases the concentration of a nervous system messenger chemical called dopamine. Higher levels of dopamine improve many cognitive processes.

Yes, generic Selegiline is available.

Anipryl is given orally. Always follow the dosage instructions provided by your veterinarian. Give Anipryl in the morning for dogs. If you have difficulty giving the medication, consult your veterinarian.

For the treatment of cognitive dysfunction, it may take several weeks to see an improvement. The amount, onset, and duration of improvement varies between animals.

For treatment of Cushing's disease, most dogs respond within one to two months.

This medication comes in tablet form.


For treatment of cognitive dysfunction, the use of Anipryl may be combined with some behavior modifying techniques to help control the symptoms in your dog. Discuss, in detail, what behavior modification techniques will work on your pet.

Talk about what exams and tests your dog may need prior to and during treatment with Anipryl.

Tell your veterinarian if your pet may be pregnant, is nursing, or if you intend to breed your pet.

Notify your veterinarian of any other medications or supplements your pet is taking, and also if your pet has had any reactions to previous medications.

If you miss a dose, give it as soon as you remember. If it is 16 hours or less before the next scheduled dose, skip the one you missed and go back to the regular schedule. Do not give two doses at once.

Anipryl does not work immediately, but may need weeks to months to show improvement. Drug reactions may occur if Anipryl is given with certain other medications or flea/tick/mite products. Always ask your veterinarian before using any of these on your pet while your pet is taking Anipryl.

Not for use in animals who are hypersensitive (allergic) to it. Your veterinarian will need to perform laboratory tests to determine which type of Cushing's disease your dog has. Anipryl is not for use in dogs who have Cushing's disease caused by adrenal gland tumors or from administration of corticosteroids.

The safety of Anipryl in breeding, pregnant, or lactating animals (female dogs nursing their young) has not been determined.

Do not use this medication for the treatment of aggression.

Side effects may include loss of appetite, drooling, vomiting, diarrhea, lethargy, anemia (pale gums), disorientation, restlessness, repetitive behaviors, loss of hearing, itching, and shaking. Contact your veterinarian if your pet experiences any of these signs.

If your pet experiences an allergic reaction to the medication, signs may include facial swelling, hives, scratching, sudden onset of diarrhea, vomiting, shock, seizures, pale gums, cold limbs, or coma. If you observe any of these signs, contact your veterinarian immediately.

Store at room temperature in a tight, light-resistant, childproof container. Keep out of reach of children and pets.

Should overdose occur, you may see drooling, slow pupillary response (pupils do not get smaller in bright light), panting, dehydration, or change in behavior. Signs of overdose may not appear for 12-24 hours. An overdose is very serious; death may occur. Contact your veterinarian immediately if you see any of these signs or suspect your pet may have had an overdose.

Notify your veterinarian of any other medications, including vitamins and supplements, your pet is taking while your pet is receiving Anipryl. Do not use within 5 weeks of antidepressants such as amitriptyline, or selective serotonin reuptake inhibitors (SSRIs) such as Prozac (fluoxetine).

Do not use with meperidine or other narcotics. Do not use with phenylpropanolamine (Proin, Propalin, Cystolamine). Do not use with ephedrine or within 2-5 weeks of using other monoamine oxidase inhibitors (MAOIs) such as amitraz (an ingredient in some tick collars, and in Mitaban, a treatment for mange).

Consult your veterinarian before using other medications or tick collars along with Anipryl. Do not give your pet aged cheese in combination with Anipryl, as it can cause severe high blood pressure or death.